Our previous research has found that tonifying Qi and activating blood herbs (such as Astragalus, Codonopsis, Sanqi and Salvia) can improve cardiomyocyte diastolic function and relieve calcium overload in the artery constriction-induced HF rat model, which is mainly through regulating the activity of calcium homeostasis-related proteins, including CaMKII [8]. Here, CAMK2G is linked to hydrops fetalis.