Subjects with LFC-NAFLD had higher values of BMI, WC, blood pressure, liver enzyme profiles, blood glucose, HbA1c, fasting insulin, TG, LDL-c, CRP, and HOMA-IR and lower levels of HDL-c (all P < 0.05; Table 1), irrespective of sex. This evidence concerns the gene INS and metabolic dysfunction-associated steatotic liver disease.