PITRM1 and early-onset autosomal dominant Alzheimer disease: PITRM1 was associated with amyloidogenic neuropathy (Boczonadi and Horvath, 2016; Brunetti et al., 2016; Smith-Carpenter and Alper, 2018) and Alzheimer’s disease (Alikhani et al., 2011; Deters et al., 2017).