CEMIP may be related to brain function and development (Yoshino et al., 2017, 2018), MEK/ERK-induced Schwann-cell dedifferentiation (Boerboom et al., 2017), immune response in glioblastoma (Motaln et al., 2012), and WNT signaling (Li et al., 2017; Duong et al., 2018; Liang et al., 2018). The gene discussed is EPHB2; the disease is glioblastoma.