GSTM1 and Alzheimer disease: Although we did not assess mast cell or basophil recruitment in our current model, previous work from our group has shown, using the Basoph-8 reporter mice (67), that basophils are recruited to the skin after injection with the allergen HDM and after prolonged topical application of a vitamin D analog MC903 that induces AD-like skin inflammation (68), and these mice could be utilized in the future to further understand the role of basophils in the Hb/DBP-FITC model.