TLR7 and breast cancer: For example, an interferon cocktail along with TLR3, TLR7, and TLR8 agonists produced superior T cell mediated cytotoxicity against a breast cancer cell line (138), while the combination of TNFα, IL-1β, IFNγ, and a TLR7/8 agonist induced higher levels of the T cell chemoattractants CXCL9/10 (139).