Studies have also shown that Bmp-7 is effective in reversing both EMT and the fibrotic effect that is induced by TGF-β; this was proved by Ziesberg's lab team in 2003, who focused on chronic renal injury, and by Ying and colleagues in 2017, where they studied the inhibition of TGF-β -induced EMT using BMP-7 in breast cancer (93, 101). This evidence concerns the gene TGFB1 and breast carcinoma.