NLRP3 and pulmonary fibrosis: Moreover, Tian et al. demonstrated, in a model of bleomycin-induced pulmonary fibrosis, that the activation of the NLRP3 inflammasome leads to EMT via TGF-β, and once NLRP3 is silenced there are reduced TGF-β levels and, thus, the EMT does not occur (38).