For this reason, present relevance networks for OpG excretion and fecal score may support the previously observed correlation between clinical coccidiosis, infection with CpA and early toltrazuril treatment in suckling piglets (Mengel et al., 2012) and chickens (Alnassan et al., 2013), thereby confirming the assumption that coccidia might create a favorable environment for colonization by opportunistic gut pathogens. This evidence concerns the gene CPA1 and infection.