According to the data from this group, anti-GABA-B receptor-related encephalitis mainly occurred in middle-aged and elderly men, and sometimes exhibited acute onset, fever, cold and other symptoms before the disease onset, which itself mainly manifested as epilepsy, cognitive function decline (especially recent memory decline), mental behavioral abnormalities and character changes, normal or increased lumbar puncture pressure. The gene discussed is GABBR1; the disease is epilepsy.