ACLY and autoimmune polyendocrinopathy: Antiphospholipid syndrome (APS) is a rare systemic autoimmune disorder clinically characterized by recurrent thrombosis or pregnancy morbidity in combination with the persistent presence of circulating antiphospholipid antibody (aPL), including anticardiolipin antibody (aCL), anti-β2-glycoprotein I (anti-β2GPI), and lupus anticoagulant (LA) (Woo et al., 2010; Gomez-Puerta and Cervera, 2014; Linnemann, 2018).