Univariate analysis revealed significantly higher rates of positive NT-proBNP in patients with coronary artery disease (OR, 1.03 [1.01 to 1.06], p = 0.009), arterial hypertension (OR, 1.03 [1.01 to 1.05], p = 0.008) and atrial fibrillation (OR, 1.03 [1.01 to 1.05], p = 0.009). The gene discussed is NPPB; the disease is Hypertension.