TNF and uveitis: Noteworthy, several trials and case series have already demonstrated the effectiveness of anti-TNF-α for treating refractory uveitis (Table 1) (Kruh et al., 2014; Vallet et al., 2016), showing a reduction of inflammatory signs and relapses, as well as an increase of the likelihood of visual acuity preservation (more than 90% in some cases) and the quality of life of uveitis patients (Fabiani et al., 2019a; Leal et al., 2019; Sharma et al., 2019).