LRP4 and myasthenia gravis: Shen et al. (2013) first reported LRP4-Abs in the blood of patients with MG. Injection of LRP4-Abs into healthy mice caused typical MG symptoms, validating the involvement of LRP4-Abs in the pathogenesis of MG (Shen et al., 2013). Few studies have focused on the relationship between dysregulated miRNAs and LRP4-Abs. LRP4 is a target for miR-490-3p (Xie et al., 2019). It can also be a target of miR-196a, miR-1232, and miR-1544; however, there are no studies on the relationship between these miRNAs and LRP4 in MG (Li et al., 2015; Karakatsani et al., 2017).