LRRK2 and Parkinson disease: Furthermore, LRRK2 is upregulated in unstimulated sporadic-PD neutrophils (Atashrazm et al., 2019), B cells, T cells and non-classical monocytes which is accompanied by increased secretion of pro-inflammatory cytokines from monocytes and T cells (Cook et al., 2017) [reviewed in detail in Lee et al. (2017) and Wallings and Tansey (2019)].