Among these 37 candidate genes (36 genes from the gene‐based collapsing analysis and RYR2), we obtained information about 33 rare variants in 18 genes in this database of arrhythmia patients; these genes were SCN1A, PRKAG2, CFTR, NOS1, PIK3CB, GAD2, HIP1R, ASPH, CD163, SLC9B1, ROBO1, EPHB4, KCNV2, PPFIA1, SYT10, COG4, MMP2, and CSF2RB. In particular, rare variants in three genes, PIK3CB, GAD2 and HIP1R, were present even in patients with PSVT (Figure 6, Table 7, and supplementary Table S12). The gene discussed is COG4; the disease is cardiac arrhythmia.