It is also worth noting that a number of factors in the TME have now been implicated in the induction of LAG‐3 expression on T cells, including IL‐6, IL‐10, and tumor‐associated APC,166 and targeting these LAG‐3 inducers may also prevent suppression of antitumor T cell immunity by this checkpoint pathway. The gene discussed is LAG3; the disease is neoplasm.