Immunohistochemical characterization of CD3 (Pan‐T cells), CD8 (T‐killer cells), Foxp3 (Regulatory T cells [Tregs]), and CD163 (macrophages), as well as immune checkpoints Programmed cell death 1 (PD‐1), Programmed cell death‐ligand 1 (PD‐L1), and Tumor necrosis factor receptor superfamily member 4 (OX40), was conducted in a consecutive cohort of 56 cHCC‐ICC patients. Here, FOXP3 is linked to intrahepatic cholangiocarcinoma.