Sankpal et al. further described the usage of an extracellular-regulated kinase 2 (ERK2) binding site within the EPCAM promoter [30], while Yamashita et al. reported on the regulation of the EPCAM promoter by a Wnt-β-catenin-Tcf4 complex in hepatocellular carcinoma cells [31]. Here, EPCAM is linked to hepatocellular carcinoma.