It had been reported that CD109 mRNA was strongly expressed in cervical squamous cell carcinoma by qPCR.5 For this reason, we accordingly used C33A, C4-1, CaSki and SiHa, which are squamous cell carcinoma cell lines of uterine cervix to investigate the functional role of CD109 in cervical cancer. The gene discussed is CD109; the disease is cervical carcinoma.