Cells of the adenocarcinoma component were CAM.5.2, CK7, CK AE1/AE3, and GATA-3 positive and negative for synaptophysin, chromogranin A, parathormone, parafibromin (Fig. 4), thyroglobulin, TTF1, calcitonin, glucagon, S100, PGP-9 and Bcl-2. This evidence concerns the gene BCL2 and adenocarcinoma.