The most common of these were prostate cancer (0.4% in each arm), lung adenocarcinoma (0.4% and 0.3% in the G-CHOP and R-CHOP arms, respectively), and breast cancer (0.1% and 0.4% in the G-CHOP and R-CHOP arms, respectively). This evidence concerns the gene DDIT3 and Familial prostate cancer.