YAP1-MAML2 gene rearrangements have been recently reported in rare nasopharyngeal carcinoma [17], all of metaplastic thymomas in one study [18] and in cell lines of diverse malignancies including glioblastoma, ovarian cancer and squamous cell carcinoma of the tongue [16, 19]. The gene discussed is MAML2; the disease is tongue squamous cell carcinoma.