Per-cluster KEGG pathway over-representation analysis (See Materials and Methods; Croft et al., 2019) of genes whose expression was modulated by IFT88 depletion, identified changes to NFκB signalling (across a number of clusters), to other pro-inflammatory signalling pathways as well as enrichments for pathways associated with cancer, rheumatoid arthritis, cardiomyopathy, and processes such as ribosome biogenesis, amino acid biosynthesis and complement and coagulation (Fig. 2D). Here, NFKB1 is linked to cardiomyopathy.