NFKB1 and rheumatoid arthritis: Per-cluster KEGG pathway over-representation analysis (See Materials and Methods; Croft et al., 2019) of genes whose expression was modulated by IFT88 depletion, identified changes to NFκB signalling (across a number of clusters), to other pro-inflammatory signalling pathways as well as enrichments for pathways associated with cancer, rheumatoid arthritis, cardiomyopathy, and processes such as ribosome biogenesis, amino acid biosynthesis and complement and coagulation (Fig. 2D).