Out of the neurofilament proteins, neurofilament light (NfL) chain has been recognized as a possible marker of axonal injury in various neurological disorders [1], including multiple sclerosis [2], motor neurone disease [3, 4], frontotemporal dementia spectrum disorders [5, 6], traumatic brain injury [7], and cerebrovascular disease [8]. This evidence concerns the gene NEFL and nervous system disorder.