miR-23b expression is upregulated in EVs of metastatic bladder cancer cells than nonmetastatic cells and reduced exocytosis of miR-23b via Rab27b knockdown promotes its intracellular activity; miR-23b inhibits invasion and anoikis of metastatic bladder cancer cells, thereby reducing in vivo angiogenesis and lung colonization [206]. Here, RAB27B is linked to urinary bladder carcinoma.