A total of 159 patients were divided into MACEs group and non-MACEs group, the clinical characteristics analysis showed that MACEs group had significantly higher age, diabetes, creatinine, NT-proBNP, serum visfatin levels (all P <  0.05) and lower albumin, triglycerides, total cholesterol, LVEF (all P <  0.05) than non-MACEs group. This evidence concerns the gene NPPB and diabetes mellitus.