CLK1 and reading: We searched all the 9 genes identified in this study (CLK1, COL6A3, CD44, ARHGEF9, HKDC1, CHEK1, HNF4A, SERPINA1, CALD1) against TSVdb and downloaded the junction usage value for colon adenocarcinoma (COAD) and rectum adenocarcinoma (READ).