Furthermore, a recent randomized, controlled, triple-blinded, parallel trial study of polycystic ovarian syndrome (POCS) showed the effect of synbiotic pomegranate juice (containing inulin and three species of Lactobacillus) in terms of improving the testosterone level, body mass index, insulin, insulin resistance, weight, and waist circumference in POCS. The gene discussed is INS; the disease is polycystic ovary syndrome.