The overexpression of HMGA2 associated with the 3′-UTR deletion was found not only in MPN patients but also in those with myelodysplastic syndrome (MDS) and MDS/MPN [70,121,122,123,124,125] as well as in patients with paroxysmal nocturnal hemoglobinuria (PNH) [73] (Figure 2). The gene discussed is HMGA2; the disease is myeloproliferative neoplasm.