HMGA2 and acute lymphoblastic leukemia: As regards HMGA2, a cytogenetic analysis of abnormalities at the 12q12-q14 chromosomal locus conducted in 78 adult B- and T-cell ALL cases showed that, in 26% of cases, a submicroscopic deletion was present at the 12q14.3 locus targeting the region containing the HMGA2 gene [215].