The DataBase of Pulmonary Hypertension in the Polish Population (Baza Nadciśnienia Płucnego; BNP-PL, https://clinicaltrials.gov/ct2/show/NCT03959748) is the first multicenter prospective registry of adult and pediatric PAH and chronic thromboembolic pulmonary hypertension (CTEPH) patients created in any central-eastern European country [13]. This evidence concerns the gene NPPB and pulmonary hypertension.