SOD1 and cardiomyopathy: In the current study, Ajwa BAC significantly protected the cardiac muscles from the cardiomyopathy alterations that were induced by elevated ROS due to the antioxidant potential of Ajwa BAC active ingredients, especially Q and R. The same results were achieved by Shi et al. [31], who reported that a combined DOX and Q treatment significantly increased the superoxide dismutase (SOD) activity and reduced the heart content of malondialdehyde (MDA), which counteracted DOX induced oxidative stress.