PEBP1 and melanoma: In accordance with our histopathological results and previously published studies [14,36], we found that both RKIP mRNA and protein expression were significantly lower in melanoma cell lines than in primary cultures of melanocytes with the exception of the Mel-HO cell line; this cell line exhibited RKIP mRNA level similar to that observed on melanocytes but a reduced protein content that suggests the involvement of a post-transcriptional mechanism limiting translation.