PRKDC and gastric adenocarcinoma: In the Kai Wang's gastric adenocarcinoma cohort [20, 21, 22], the TMB of PRKDC mut+ samples is significantly higher than in the PRKDC mut− samples only in the MSI‐H subtypes (median nonsynonymous mutations 1467 vs. 553, P < 0.01; Fig. S2).