Patients with pre-sarcopenia had lower body mass index than those without, and had more proportion of grade 2 and grade 3 of albumin to bilirubin grade , as well as proportions of alpha-fetoprotein over 20 ng/mL in these patients; finally, the pre-treatment platelet was lower in this group than in the non-pre-sarcopenia group. The gene discussed is AFP; the disease is sarcopenia.