The eQTL data indicate that all of the eight SNPs are eQTL for multiple genes, including GSDMB and ORMDL3 that are expressed in lung epithelial cells (https://research.cchmc.org/pbge/lunggens/mainportal.html) and influence asthma pathogenesis (Supplementary Table S1) (46,47). This evidence concerns the gene GSDMB and asthma.