PYCR1 was shown to regulate NSCLC cell migration and invasion, and the expression of the typical epithelial-mesenchymal transition markers E-cadherin, Vimentin, N-cadherin, and Snail1, suggesting that PYCR1 may be critical for NSCLC aggressiveness and a potential target for treating NSCLC (39). The gene discussed is SNAI1; the disease is non-small cell lung carcinoma.