The same report also indicated that most of the lung cancer cell lines showed down-regulation of IGFBP7 compared to normal tissues, and there was no difference in the expression pattern of IGFBP7 between small cell lung cancer (SCLC) cell lines and non-small cell lung cancer cell lines (NSCLC) (87). The gene discussed is IGFBP7; the disease is non-small cell lung carcinoma.