Caspase-3 positive cells in an OVCAR8 tumor grown in an NSG mouse (Figure 6F, upper row) and in a PDX-4 tumor grown in an NSG mouse (Figure 6F, lower row) are shown by arrows (20 ×) in mice treated with the 4D12G1 mAb (Figure 6F, right column) compared to mice treated with an isotype control mAb (Figure 6F, left column). Here, CASP3 is linked to neoplasm.