TGM2 and cancer: In fact, emerging studies revealed that miR-532-3p could act as a cancer promoter or inhibitor in different kinds of cancers, such as ovarian cancer (Zhou et al., 2018), hepatocellular carcinoma (Wang et al., 2019) and et al. For example, Gu’s research revealed that miR-532-3p could suppress the colorectal cancer progression via regulating ETS1/TGM2 axis-mediated Wnt/β-catenin signaling pathway (Gu et al., 2019).