After upregulating miR-532-3p expression, the epithelial mark (E-ca) was again reduced, while mesenchymal markers including N-ca and Vimentin proteins, were consistently increased in OE_ circRNA_103809 breast cancer cells, in both circRNA_103809-overexpressed MDA-MB-157 and MDA-MB-231 cells (Figure 8C). This evidence concerns the gene VIM and breast cancer.