Direct CC chemokine antibodies targeting is an option but the main target are CC chemokine receptor such as CCR1, CCR2, CCR4, CCR5, and CCR7 by monoclonal antibodies inhibitors or antagonism molecules (118) for example, Maraviroc is a CCR5 receptor antagonism that decrease metastasis in breast (119) and gastric cancer (120) and provoke remission in pancreatic and liver cancer by apoptosis induction (20). Here, CCR7 is linked to gastric cancer.