CAV1 and neoplasm: Astragaloside IV (Astragalus membranaceus extract) suppresses tumor progression through inhibiting Akt/GSK-3β/β-catenin signaling axis and enhances chemosensitivity via targeting caveolin-1 (CAV-1), which led to oxidative stress (Jia et al., 2018; Zheng et al., 2018).