Depletion of Axl in FAKKO pericytes reduced the enhanced tumour growth and angiogenesis observed in mice co-injected with FAK-null;Cas9 pericytes (Fig. 3e) suggesting that the elevated p-Axl in FAKKO pericytes is likely involved in the enhanced tumour growth in pdgfrβcre+;fakfl/fl mice. This evidence concerns the gene AXL and neoplasm.