PTK2 and neoplasm: Similar to our mouse data, we showed that a high proportion of pericyte FAK-undetectable blood vessels (i.e., when more than 50% of the vessels are pericyte FAK-undetectable) stratifies patients into those with increased blood vessel density (Fig. 5c), enhanced tumour burden (identified by increasing Breslow thickness) (Fig. 5d) and increased metastasis (Fig. 5e).