In line with our observations, it has been reported that ASCL1 (and not NEUROD1) is physically recruited on DARPP-32 promoter in ASCL1-high human SCLC cell lines.32 In a subset of SCLC patients with high tumoural t-DARPP expression, we show that the Notch signalling gene set was highly regulated, among which ASCL1 was the top differentially expressed transcript. Here, PPP1R1B is linked to small cell lung carcinoma.