Because tumors can modulate immune cells to acquire a tumor-associated immunosuppressive phenotype, we also determined the expression of immunomodulatory markers including programmed death ligand-1(PDL-1), Fas ligand (FasL), and Cytotoxic T lymphocyte antigen4- (CTLA-4) on the GBex-treated macrophages. The gene discussed is CD274; the disease is neoplasm.