Further analysis with murine mixed glia derived from Becn1+/− and Becn1+/+ pups infected with ZIKV and exposed to viral proteins showed a significant increase in viral replication, which correlated with an increase in viral-induced cytokine and chemokine (Figure 4), thus supporting a link between Beclin1 and ZIKV infection. Here, BECN1 is linked to Zika virus infectious disease.