Surprisingly, a very significant difference was observed concerning the expression of BMP-2 (micro+ 157.0 ± 13.25; micro− 121.9 ± 12.38) and nBMP-2 (micro+ 273.2 ± 16.60; micro− 51.40 ± 10.20) in breast lesions with or without calcifications (micro+ BMP-2 vs. nBMP-2 p < 0.0001; micro− BMP-2 vs. nBMP-2 p < 0.0001) (Figure 3A–E). This evidence concerns the gene BMP2 and calcification.