They concluded that “the quality and quantity of the host response to oral bacteria may be an exposure more relevant to systemic atherothrombotic coronary events than clinical measures”: the presence of serum antibodies to P. gingivalis increased the risk of stroke (1.6–2.3 times), while periodontal diseases are associated with elevated systemic levels of high-sensitivity plasma C-reactive protein (CRP). This evidence concerns the gene CRP and stroke disorder.