Even more important is the fact that GPR107 expression levels were directly associated with other relevant clinical parameters of PCa-aggressiveness (i.e., tumor stage and vascular invasion and presence of metastasis) as well as with the expression levels of key molecular markers of PCa-aggressiveness (e.g., CDK2, VEGFR, IL6R) [44,45,46]. This evidence concerns the gene CDK2 and neoplasm.