GPR107 and neoplasm: Moreover, these results have special relevance because GPR107 silencing was able to consistently decrease SST5TMD4 expression in all the AI-PCa models tested herein, in which we previously demonstrated that overexpression of SST5TMD4 is directly associated to the inefficiency of SSA therapy (i.e., octreotide treatment) in PCa cells and other tumor types [11,32,60,61,62] as well as of other drugs currently used for the treatment of PCa (i.e., abiraterone or enzalutamide) [11].