RALBP1 and cancer: Together, these prior studies established that Rlip is a multifunctional stress-responsive and anti-apoptotic protein that functions as a nexus between the biochemical pathways that utilize GSH to remove electrophilic endobiotic and xenobiotic toxins from cells, and the cancer-promoting signaling mechanisms that lie downstream of the ligand–receptor signaling networks that are regulated by CDE [34].