TLR4 and B-cell chronic lymphocytic leukemia: Studies involving patients with CLL [46], gastric [47,49], and pancreatic [48] cancers were also included in the current review and found specific polymorphisms of genes involved in inflammation pathways (e.g., TLR4) and cell proliferation or apoptosis (e.g., NF-kB, TRAF3, CSF1/2, K-ras oncogene) positively associated with higher intake of n-3 LC-PUFA and decreased cancer risk.