Cui et al. (2016) conducted a retrospective cohort investigating the association between fatty acid desaturase (FADS) rs174537 and Cg27386326 methylation status with n-3 LC-PUFA composition and markers of n-3 LC-PUFA biosynthesis in specimens from 60 PCA patients undergoing radical prostatectomy. Here, SCD is linked to posterior cortical atrophy.