Overall, the association between n-3 LC-PUFA intake (and/or fish intake) and breast cancer risk is consistent with those reported by Zheng et al.’s meta-analysis [58] and found that higher dietary n-3 LC-PUFA was associated with a lower risk of breast cancer, especially in ER+/PR patients, although no association was observed for fish intake alone. The gene discussed is ESR1; the disease is breast cancer.