The final model was fitted on 1608 TB cases, mortality was significantly associated with age above 70 years (p = .001), alcohol abuse (p < .001), CCI ≥2 (p = .01), weight loss (p = .02), anemia (p = .01) and C-reactive protein above 100 mg/L at time of diagnosis (p < .001). The gene discussed is CRP; the disease is anemia (phenotype).